| Mikel John Obi | Chelsea F.C. | 2006–2017 | 249 | 1 |
| Victor Moses | Crystal Palace F.C., Liverpool F.C., Chelsea F.C. | 2007–2021 | 164 | 19 |
| Manuel Akanji | Manchester City F.C. | 2022–2026 | 85 | 2 |
| Nwankwo Kanu | Arsenal F.C. | 1999–2004 | 119 | 30 |
| Obafemi Martins | Newcastle United F.C. | 2006–2009 | 88 | 28 |
| Yakubu | Coventry City F.C., Everton F.C. | 2007–2017 | 85 | 25 |
| Ademola Lookman | Everton F.C., Fulham F.C. | 2017–2021 | 70 | 5 |
| Alex Iwobi now | Everton F.C., Fulham F.C., Arsenal F.C. | 2015–now | 326 | 35 |
| Jay-Jay Okocha | Hull City A.F.C. | 2007–2008 | 18 | 0 |
| Joseph Yobo | Everton F.C. | 2002–2012 | 220 | 8 |
| Kelechi Iheanacho | Manchester City F.C. | 2015– | – | – |
| William Troost-Ekong | Tottenham Hotspur F.C. | 2011–2013 | 0 | 0 |
| Victor Anichebe | Sunderland A.F.C., Everton F.C. | 2006–2017 | 149 | 21 |
| Celestine Babayaro | Chelsea F.C., Newcastle United F.C. | 1997–2008 | 179 | 6 |
| Ola Aina | Chelsea F.C., Nottingham Forest F.C., Hull City A.F.C. | ?– | – | – |
| Shola Ameobi | Crystal Palace F.C., Newcastle United F.C. | 2000–2015 | 316 | 53 |
| Taiwo Awoniyi now | Liverpool F.C., Nottingham Forest F.C. | 2015–now | 0 | 0 |
| Arnaut Danjuma | AFC Bournemouth, Everton F.C., Tottenham Hotspur F.C. | 2019–2024 | 70 | 17 |
| Daniel Amokachi | Everton F.C. | 1994–1996 | 43 | 10 |
| Finidi George | Ipswich Town F.C. | 2001–2003 | 35 | 7 |
| Dickson Etuhu | Sunderland A.F.C., Manchester City F.C., Fulham F.C. | 2000–2012 | 123 | 4 |
| Kenneth Omeruo | Chelsea F.C. | 2012–2019 | 0 | 0 |
| Nedum Onuoha | Sunderland A.F.C., Manchester City F.C. | 2004–2012 | 126 | 4 |
| Tariq Lamptey now | Chelsea F.C., Brighton & Hove Albion F.C. | 2019–now | 1 | 0 |
| Sammy Ameobi | Newcastle United F.C. | 2010– | – | – |
| Sone Aluko | Hull City A.F.C., Fulham F.C. | 2012– | – | – |
| Emmanuel Dennis | Nottingham Forest F.C. | ?– | – | – |
| Destiny Udogie now | Tottenham Hotspur F.C. | 2022–now | 28 | 2 |
| Frank Onyeka | Brentford F.C. | ?– | – | – |
| Henry Onyekuru | Everton F.C. | ?– | – | – |
| Calvin Bassey | Fulham F.C. | ?– | – | – |
| Semi Ajayi | Arsenal F.C. | 2013–2015 | 0 | 0 |
| Ade Akinbiyi | Crystal Palace F.C., Brighton & Hove Albion F.C. | 1994–2003 | 38 | 11 |
| Seyi Olofinjana | Hull City A.F.C. | 2009–2013 | 34 | 1 |
| Efan Ekoku | AFC Bournemouth, Brentford F.C. | 1990–2003 | 62 | 21 |
| Kelechi Nwakali | Arsenal F.C. | 2016–2019 | – | – |
| Chiedozie Ogbene | Brentford F.C. | ?– | – | – |
| Hope Akpan | Everton F.C., Hull City A.F.C. | 2009–2011 | 2 | 0 |
| Kelvin Etuhu | Manchester City F.C. | 2006–2011 | 10 | 1 |
| Dele Adebola | Crystal Palace F.C., Nottingham Forest F.C., Coventry City F.C., Hull City A.F.C. | 2002–2012 | 274 | 41 |
| Chidiebere Nwakali | Manchester City F.C. | ?– | – | – |
| Emmanuel Sarki | Chelsea F.C. | 2006–2010 | 0 | 0 |
| Rinsola Babajide now | Crystal Palace F.C., Liverpool F.C. | 2018–now | 33 | 21 |
| Eric Obinna Chukwunyelu | Arsenal F.C. | 1998–2000 | 0 | 0 |
| Reuben Agboola | Sunderland A.F.C. | 1985–1991 | 140 | 0 |
| Sam Sodje | Leeds United F.C., Brentford F.C. | 2004–2009 | 91 | 12 |
| David Adekola | AFC Bournemouth, Brighton & Hove Albion F.C. | 1994–1996 | 2 | 0 |
| Gboly Ariyibi | Leeds United F.C. | 2013–2014 | 2 | 0 |
| Emeka Ifejiagwa | Brighton & Hove Albion F.C. | 1998–1999 | 2 | 1 |
| Enoch Showunmi | Leeds United F.C. | 2008–2010 | 15 | 2 |
| Ademola Bankole | Brentford F.C. | 2005–2006 | 6 | 0 |
| John Chiedozie | Tottenham Hotspur F.C. | 1984–1988 | 53 | 12 |
| Kareem Kazeem | Fulham F.C. | ?– | – | – |
| Michael Uwezu | Fulham F.C. | 2009–2010 | 0 | 0 |
| Fola Onibuje | Brentford F.C. | 2006–2006 | 2 | 0 |
| Jide Olugbodi | Brentford F.C. | 2003–2003 | 2 | 0 |
| Musa Yahaya | Tottenham Hotspur F.C. | 2014– | – | – |
| Joe Omigie | Brentford F.C. | 1994–1998 | 24 | 2 |
